Chemiball Hazard
Overview
Chemiball Hazard is an orb effect that creates poison slime on pegs it touches, functioning as an alternative method to apply ongoing damage similar to Spinfection but by sliming multiple pegs rather than targeting a single enemy. The slimed pegs deal recurring poison damage each turn until the slime is removed; however, popping any slimed peg removes the poison from that peg and the slime does not refresh on a popped peg.
Chemiball Hazard scales well with multiball generation and peg-modifying effects. Orbs and relics that produce multiple balls—such as 

Peg upgrade and downgrade modifiers interact strongly with Chemiball Hazard’s poison damage. Upgrades and downgrades modify the per-peg poison damage according to the game's formulas: damage = 10 + U for an upgrade value U, and damage = 10 + |2 × W| for a downgrade value W. Because of this, effects that increase or decrease peg values (for example, 
Practical notes for use and strategy:
- Prioritize combinations with multiball sources to maximize the number of slimed pegs and cumulative poison damage.
- Avoid popping slimed pegs when possible, since each popped peg permanently loses its slime and its ongoing damage contribution.
- If a playstyle frequently requires popping many pegs (for direct ball damage or clears), reconsider relying on Chemiball Hazard as your primary damage engine or take relics that upgrade pegs to offset the loss.
- Chemiball Hazard does not replace Spinfection; it can be stacked with Spinfection generation to add additional per-turn damage on top of infection-based effects.
- Consider synergy with peg-upgrading relics and orbs to exploit the damage-bonus formulas and amplify the poison per peg.
The name "Chemiball Hazard" is a portmanteau of "chemical hazard" and "ball."